Proteomic Analyses of Agkistrodon contortrix contortrix Venom Using 2D Electrophoresis and MS Techniques
نویسندگان
چکیده
منابع مشابه
Proteomic Analyses of Agkistrodon contortrix contortrix Venom Using 2D Electrophoresis and MS Techniques
Snake venom is a complex mixture of proteins and peptides which in the Viperidae is mainly hemotoxic. The diversity of these components causes the venom to be an extremely interesting object of study. Discovered components can be used in search for new pharmaceuticals used primarily in the treatment of diseases of the cardiovascular system. In order to determine the protein composition of the s...
متن کاملStructure of acostatin, a dimeric disintegrin from Southern copperhead (Agkistrodon contortrix contortrix), at 1.7 Å resolution
Disintegrins are a family of small (4-14 kDa) proteins that bind to another class of proteins, integrins. Therefore, as integrin inhibitors, they can be exploited as anticancer and antiplatelet agents. Acostatin, an alphabeta heterodimeric disintegrin, has been isolated from the venom of Southern copperhead (Agkistrodon contortrix contortrix). The three-dimensional structure of acostatin has be...
متن کاملReproduction in female copperhead snakes (Agkistrodon contortrix): plasma steroid profiles during gestation and post-birth periods.
We investigated levels of plasma progesterone (P4), 17β-estradiol (E2), testosterone (T), and corticosterone (CORT) during gestation and post-birth periods in wild-collected female copperhead snakes (Viperidae; Agkistrodon contortrix). We also sought to determine whether CORT levels at (or near) birth dramatically increase and were correlated with duration of labor and litter size. Specifically...
متن کاملPost-fight levels of plasma lactate and corticosterone in male copperheads, Agkistrodon contortrix (Serpentes, Viperidae): differences between winners and losers.
During the mating seasons (late summer and spring), male copperheads (Agkistrodon contortrix; Serpentes, Viperidae) engage in aggressive physical interactions for priority of access to females. These fights generally involve two individuals and are characterized by prominent vertical displays, a high degree of physical contact, and the absence of biting. Ritualized aggression does not occur in ...
متن کاملSpatial ecology and multi-scale habitat selection of the Copperhead (Agkistrodon contortrix) in a managed forest landscape
http://dx.doi.org/10.1016/j.foreco.2017.02.041 0378-1127/ 2017 Elsevier B.V. All rights reserved. ⇑ Corresponding authors at: 3500 John A. Merritt Blvd, Nashville, TN 37209, USA (W.B. Sutton). 4900 Meridian Street North, Huntsville, AL 35811, USA (Y. Wang). E-mail addresses: [email protected] (W.B. Sutton), [email protected] (Y. Wang). William B. Sutton a,b,⇑, Yong Wang a,⇑, Callie J. Schwei...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Toxins
سال: 2016
ISSN: 2072-6651
DOI: 10.3390/toxins8120372